透明质酸的作用机制及临床应用研究进展
投稿时间:2021-08-02  修订日期:2021-10-11  点此下载全文
引用本文:蔡同凯,刘谋治,邓婕,曹永兵,阎澜.透明质酸的作用机制及临床应用研究进展[J].药学实践杂志,2022,40(2):103~107,131
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作者单位E-mail
蔡同凯 海军军医大学药学系, 上海 200433
上海迪亚凯特生物医药科技有限公司, 上海 201203 
 
刘谋治 上海迪亚凯特生物医药科技有限公司, 上海 201203  
邓婕 上海中医药大学附属中西医结合医院脉管病研究所, 上海 200082  
曹永兵 上海中医药大学附属中西医结合医院脉管病研究所, 上海 200082  
阎澜 海军军医大学药学系, 上海 200433 ylan20001228@sina.com 
中文摘要:透明质酸广泛存在于人体中,是细胞外基质的重要成分,具有独特的流体力学性质、良好的黏弹性和应变性。目前透明质酸被广泛用于生物材料、药物靶向制剂、美容以及腹部手术后预防黏连等。随着透明质酸应用范围的扩展及新型医用材料的不断涌现,近年来对透明质酸的研究日益增加。本文对透明质酸的临床应用及其作用机制进行综述,以期为透明质酸产品的进一步研发和安全应用提供参考。
中文关键词:透明质酸  生物材料  药物靶向制剂  美容  预防手术后黏连
 
Research progress on action mechanism and clinical application of hyaluronic acid
Abstract:Hyaluronic acid is widely present in the human body. It is an important component of extracellular matrix. It has unique hydrodynamic properties, good viscoelasticity and strain properties. At present, hyaluronic acid has been widely used in biomaterials, targeted-drug preparations, cosmetics and prevention of adhesion after abdominal surgery. With the expansion of the application scope of hyaluronic acid and the continuous emergence of new medical materials, the research on hyaluronic acid has been increasing in recent years. This paper reviews the clinical application of hyaluronic acid and its mechanism, in order to provide reference for the further development and safe application of hyaluronic acid products.
keywords:hyaluronic acid  biomaterials  drug targeted preparations  cosmetology  prevent postoperative adhesion
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