| 聚丙烯酸型高吸水树脂缓泻作用研究 |
| 投稿时间：2004-02-06 点此下载全文 |
| 引用本文：张辉,檀德宏,韩俊雁.聚丙烯酸型高吸水树脂缓泻作用研究[J].药学实践杂志,2004,(5):274~275 |
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| 中文摘要:目的 探讨聚丙烯酸型高吸水树脂的缓泻作用。方法 采用小鼠胃肠推进运动实验、小鼠小肠保水实验和对小鼠便秘模型作用实验,并对实验数据进行统计分析。结果 聚丙烯酸型高吸水树脂可使小肠推进距离和小肠推进率增加并显著高于对照组(P<0.01);聚丙烯酸型高吸水树脂组小肠重量明显高于空白对照组(P<0.01),表明聚丙烯酸型高吸水树脂可增加肠道水分;聚丙烯酸型高吸水树脂使便秘小鼠排便粒数显著高于便秘模型组(P<0.01)。结论 聚丙烯酸型高吸水树脂在一定剂量下具有缓泻作用。 |
| 中文关键词:聚丙烯酸型高吸水树脂 缓泻作用 便秘 |
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| Laxative effect of sodium polyacrylate |
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| Abstract:Objective To investigate if sodium polyacrylate, a kind of superabsorbent polymer widely used in infant diaper and feminine napkin, has laxative effect. Methods Mice bowel motion test and keeping water test were carried out and mice constipation models were treated. Results It was found that sodium polyacrylate could increase intestine motion significantly and make intestine keeping more water than placebo,and treat constipation effectively. Conclusion Sodium polyacrylate has laxative effect. |
| keywords:sodium polyacrylate laxative constipation |
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