抗生素联合抗菌作用试验观察
投稿时间:2003-10-28    点此下载全文
引用本文:国建秋,徐卫宾.抗生素联合抗菌作用试验观察[J].药学实践杂志,2004,(2):81~82
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作者单位
国建秋 山东省济宁市药品检验所, 山东 济宁 272000 
徐卫宾 山东省济宁市药品检验所, 山东 济宁 272000 
中文摘要:目的 为减少抗生素耐药性的产生,寻找适合的抗生素联合用药方式。方法 应用十种常见抗生素分别单独或联合作用于7种常见的致病菌,测定其最低抑菌浓度(MIC)。结果与结论 红霉素对各种致病性球菌有较强的抑菌能力,庆大霉素对各种致病杆菌的作用较强;红霉素或庆大霉素与其它抗生素联用,大多能获得较明显的协同作用,但庆大霉素不宜与青霉素类联合应用。
中文关键词:抗生素  致病菌  协同作用  拮抗作用
 
The study of the synergy effect of antibiotics in vitro
Abstract:Objective Ques suitable associating medications to reduce the drug tolerance of antibiotics. Methods Use ten species of common antibiotics alone or synapse to compose with seven species of common bacteria which causing diseases. Results and Conclusion Erythrocin has a strong inhibition action to pathogenicity coccus. Gentamycin has a strong inhibition action to pathogenicity rods. Most antibiotics have transparent synergistic actions with erythrocin or gentamycin. But gentamycin unite with penicillin is not suitable.
keywords:antibiotics  the bacteria which causing disease  synergistic action  antagonistic action
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