活血化瘀法治疗血管性痴呆的研究进展
投稿时间:2024-08-23  修订日期:2024-10-21  点此下载全文
引用本文:段禹,刘爱军.活血化瘀法治疗血管性痴呆的研究进展[J].药学实践杂志,2025,43(4):151~155
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作者单位E-mail
段禹 山东中医药大学药学院, 山东 济南 250355
上海中医药大学附属岳阳中西医结合医院药学研究室, 上海 200437 
 
刘爱军 山东中医药大学药学院, 山东 济南 250355
上海中医药大学附属岳阳中西医结合医院药学研究室, 上海 200437 
mrliuaijun@163.com 
基金项目:国家自然科学基金(82273984);上海中医药大学附属岳阳中西医结合医院基金(2021yygm01);国家重点研发计划项目(YS2019YFC170045)
中文摘要:活血化瘀法是指使用具有消散作用,能祛除体内瘀血的中药治疗瘀血病证的方法,具有畅通血脉、消散瘀滞、调经止痛的作用,广泛应用于瘀血导致的胸痹心痛、痴呆、月经不调等病症,常用药物有丹参、三七、川芎、郁金等。活血化瘀类药物普遍具有改善微循环、舒张血管、抑制血栓素形成、抑制血小板聚集等作用,在冠心病、心绞痛、血管性痴呆等疾病的血瘀证治疗方面具有较好的疗效。该文通过对活血化瘀类药物治疗血管性痴呆的中医和现代医学研究进展进行综述,以期为临床应用活血化瘀法治疗血管性痴呆提供参考。
中文关键词:活血化瘀  血管性痴呆  瘀阻脑络  丹参  虎杖  川芎  郁金
 
Research progress on the treatment of vascular dementia by promoting blood circulation and removing blood stasis
Abstract:The method of promoting blood circulation and removing blood stasis refers to the use of traditional Chinese medicine with a dispersing effect that can eliminate blood stasis in the body to treat the syndrome of blood stasis, which has the effects of unblocking blood vessels, dissipating stasis, regulating menstruation and relieving pain and are widely used for conditions such as chest tightness, heartache, dementia, menstrual disorders caused by blood stasis. Common medicines include Salvia miltiorrhiza Bunge, Panax notoginseng (Burkill), Ligusticum chuanxiong Hort, Radix Curcumae, etc. Blood activating and stasis removing drugs generally have the effects of improving microcirculation, relaxing blood vessels, inhibiting thromboxane formation, and inhibiting platelet aggregation. They have good therapeutic effects on blood stasis syndrome in diseases such as coronary heart disease, angina pectoris, and vascular dementia. The research progress on traditional Chinese medicine and modern medicine on the treatment of vascular dementia with blood activating and stasis removing drugs were reviewed, in order to provide reference for the clinical application of blood activating and stasis removing methods in the treatment of vascular dementia.
keywords:promoting blood circulation and removing blood stasis  Vascular dementia  Stagnation of the brain meridian  Salvia miltiorrhiza Bunge  Reynoutria japonica Houtt.  Ligusticum chuanxiong Hort  Radix Curcumae
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