铜绿假单胞菌合并按蚊伊丽莎白菌肺部感染的病例分析
投稿时间:2023-10-22  修订日期:2024-03-19  点此下载全文
引用本文:尹小娟,台力丽,肖俊峰,季波.铜绿假单胞菌合并按蚊伊丽莎白菌肺部感染的病例分析[J].药学实践杂志,2024,42(5):223~226
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作者单位E-mail
尹小娟 佛山市禅城区人民医院, 广东 佛山, 52800  
台力丽 南部战区总医院药学部, 广东 广州, 510000  
肖俊峰 南部战区总医院药学部, 广东 广州, 510000  
季波 南部战区总医院药学部, 广东 广州, 510000 jbjenny@sina.com 
中文摘要:目的 探讨脑出血患者出现铜绿假单胞菌合并按蚊伊丽莎白菌感染的危险因素及抗菌药物治疗方案。方法 临床药师参与1例脑出血患者铜绿假单胞菌合并按蚊伊丽莎白菌肺部感染的治疗过程,通过查阅文献资料,并结合患者病情、病史、用药史及相关检查结果,分析按蚊伊丽莎白菌致病的危险因素并提出抗菌药治疗方案。结果 临床药师基于感染部位、混合细菌感染特点、抗菌药动学/药效学特性等,在抗感染方案调整为临床医师提出的用药建议后,患者全身感染得到有效控制。 结论 按蚊伊丽莎白菌为条件致病菌,毒力较低,不易感染健康人群。但当患者免疫力低时易转化为致病菌,需引起重视。
中文关键词:按蚊伊丽莎白菌  铜绿假单胞菌  肺部感染
 
Analysis of pulmonary infection of Pseudomonas aeruginosa combined with Elizabethkingia anophelis
Abstract:Objective To investigate the risk factors of infection of Pseudomonas aeruginosa combined with Elizabethkingia anophelis in patients with cerebral hemorrhage and the antimicrobial treatment plan. Methods Clinical pharmacists participated in the treatment of pulmonary infection caused by Pseudomonas aeruginosa combined with Elizabethkingia anophelis in a patient with cerebral hemorrhage. The risk factors of Elizabethkingia anophelis infection and antimicrobial treatment plan were analyzed by referring to literature and combining the patient’s condition, medical history, drug use history and related examination results. Results Based on the infection site, the characteristics of mixed bacterial infection, and the metabolic/pharmacodynamic characteristics of antimicrobial agents, clinical pharmacists made drug recommendations for clinicians in the adjustment of anti-infection protocols, and patients’ systemic infections were effectively controlled. Conclusion Elizabethkingia anophelis is a conditional pathogen with low virulence and is not easy to infect healthy people. When the patient's immunity is low, it is easy to transform into pathogenic bacteria, which should be paid attention to.
keywords:Elizabethkingia anophelis  Pseudomonas aeruginosa  pulmonary infection
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