| 中药成分调控肠道菌群影响肠吸收转运的研究进展 |
| 投稿时间：2023-03-08 修订日期：2024-01-12 点此下载全文 |
| 引用本文：江骏,陈立,李众,刘金阁,齐天,周婷婷.中药成分调控肠道菌群影响肠吸收转运的研究进展[J].药学实践杂志,2024,42(3):89~93,120 |
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| 中文摘要:概括介绍中药成分调控肠道菌群影响肠道吸收转运作用的国内外研究进展，为后续以肠道菌群为靶点研究临床合理用药提供帮助。通过查阅近年来肠道菌群与肠道吸收转运方面的文献，分析总结现有相关研究，阐述中药成分调控肠道菌群对药物吸收转运的作用机制。研究发现中药成分改变肠道菌群进而影响肠道屏障功能和吸收转运，对临床合理用药具有重要意义。 |
| 中文关键词:肠道菌群 中药成分 肠道屏障 吸收转运 |
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| Research progress on the regulation of intestinal flora and effect on intestinal absorption and transport by TCM components |
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| Abstract:The domestic and international research progress on the regulation of gut microbiota by Traditional Chinese Medicine (TCM) ingredients and their impact on intestinal absorption and transportation were summarized, which provided assistance for subsequent clinical rational drug use targeting gut microbiota. Literature on the relationship between gut microbiota and intestinal absorption and transportation in recent years were reviewed and analyzed, and the mechanism of TCM ingredients regulating gut microbiota on drug absorption and transportation was elucidated. Research has found that TCM ingredients alter gut microbiota, thereby affecting intestinal barrier function and absorption of transport proteins, which is of great significance for rational clinical medication. |
| keywords:intestinal microbiota Traditional Chinese Medicine ingredients intestinal barrier absorption transport |
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