| 三斑海马的化学成分研究 |
| 投稿时间：2022-12-14 修订日期：2023-05-13 点此下载全文 |
| 引用本文：乔方良,夏天爽,张成中,蒋益萍,辛海量.三斑海马的化学成分研究[J].药学实践杂志,2023,41(9):540~543,560 |
| 摘要点击次数: 457 |
| 全文下载次数: 914 |
|
| 基金项目:国家重点研发计划（2019YFC1711000） |
|
| 中文摘要:目的 研究三斑海马的化学成分。方法 采用乙醇提取和硅胶柱色谱、Sephadex LH-20葡聚糖凝胶柱色谱、反相C18柱色谱等方法对三斑海马化学成分进行分离纯化，通过理化性质、波谱数据和文献对比，对得到的化合物进行结构鉴定。结果 从三斑海马中分离得到8个化合物，分别鉴定为：L-苯丙氨酸(1)、丙氨酸(2)、肌苷(3)、胆固醇(4)、N-乙酰基酪胺(5)、尿嘧啶(6)、D-甘露醇(7)、河豚素(8)。结论 化合物5、7、8为首次从三斑海马中分离得到。 |
| 中文关键词:三斑海马 化学成分 提取分离 结构鉴定 |
| |
| Study on chemical constituents of Hippocampus trimaculatus Leach |
|
|
| Abstract:Objective To study the chemical constituents of Hippocampus trimaculatus Leach. Methods After extracted with ethanol, Hippocampus trimaculatus Leach was isolated and purified by silica gel column chromatography, Sephadex LH-20 gel column chromatography, and reversed-phase C18 column chromatography. The structures of compounds were identified by physical and chemical properties, spectral data and literature comparison. Results Eight compounds were isolated from Hippocampus trimaculatus Leach and identified as L-phenylalanine (1), alanine (2), inosine (3), cholesterol (4), N-acetyltyramine (5), uracil (6), D-mannitol (7), tetrodoine (8), respectively. Conclusion Compounds 5, 7, 8 are isolated from Hippocampus trimaculatus Leach for the first time. |
| keywords:Hippocampus trimaculatus Leach chemical constituents extraction and separation structure identification |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
| 关闭 |
|
|
|
