| 玉米须黄酮化学成分与药理作用研究进展 |
| 投稿时间：2023-09-16 修订日期：2024-01-10 点此下载全文 |
| 引用本文：周丽城,欧已铭,王园.玉米须黄酮化学成分与药理作用研究进展[J].药学实践杂志,2025,43(2):51~58 |
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| 中文摘要:玉米须是玉米的干燥花柱和柱头，我国常用传统中药，具有平肝利胆、利尿消肿之功效。玉米须还被广泛用作茶和功能食品。玉米须富含黄酮类化合物，为玉米须中主要的生物活性成分。近年来，玉米须黄酮的化学、分析、药理、药代动力学及安全性评价方面的研究取得了较多的进展。黄酮化学成分的研究丰富了玉米须中黄酮类化合物的种类，多项药理学研究证实和拓展了玉米须黄酮的功效，安全性评价为玉米须黄酮的安全应用提供了理论依据。通过文献查阅，综述近10年来玉米须黄酮的提取工艺、成分表征、含量测定、药理作用及安全性等方面的研究进展，为玉米须黄酮的进一步开发及应用提供依据。 |
| 中文关键词:玉米须 黄酮 化学成分 药理作用 安全性 |
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| Flavonoids from Corn Silk （Zea mays L.） and its pharmacological effects |
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| Abstract:Corn silk, a Traditional Chinese Medicine, has the effect of calming liver, cholagogue, detumescence and diuresis. Corn silk is also widely used as tea and functional food. Natural flavonoids have multiple biological activities, which are also the main bioactive components of corn silk. In the past decade, many new advances have been made in the chemistry, analysis, pharmacology, pharmacokinetics, and safety evaluation of corn silk flavonoids. The chemical composition research of flavonoids has enriched the variety of flavonoids in corn silk. Pharmacological studies have confirmed and expanded the efficacy of corn silk flavonoids. And safety evaluation has provided a theoretical basis for the safe application of corn silk flavonoids. Through literature search, the extraction, separation, compositional analysis, content determination, pharmacological effect, pharmacokinetics, and safety research progress of corn silk flavonoids in the past ten years were reviewed in this paper. |
| keywords:corn silk flavonoid chemical constituents pharmacological effects safety |
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