| 菸花苷对缺血性脑卒中大鼠的长期保护作用 |
| 投稿时间：2022-01-21 修订日期：2022-03-28 点此下载全文 |
| 引用本文：严啸东,王业晴,李炳锋,郭美丽.菸花苷对缺血性脑卒中大鼠的长期保护作用[J].药学实践杂志,2022,40(3):226~230,258 |
| 摘要点击次数: 830 |
| 全文下载次数: 714 |
|
| 基金项目:国家科技重大专项（2009ZX09102-131） |
|
| 中文摘要:目的 探讨菸花苷对缺血性脑卒中大鼠的长期保护作用。方法 建立大鼠脑缺血模型，观察菸花苷对于大鼠长期生存率、神经系统功能、体重及脑神经元的影响。结果 菸花苷可以显著提高脑缺血大鼠的长期生存率，促进大鼠体重增加，减轻脑组织病理损伤，维持脑神经元形态及神经系统功能。结论 菸花苷具有明显的对缺血性脑卒中大鼠的长期保护作用，其作用机制可能与保护脑神经元结构和功能有关。 |
| 中文关键词:菸花苷 缺血性脑卒中 神经保护 病理 |
| |
| Long-term protective effects of the nicotiflorin on ischemic stroke rats |
|
|
| Abstract:Objective To investigate the long-term protective effects of the nicotiflorin on ischemic stroke rats. Methods Ischemic stroke model in rats was established for this study. The effects of nicotiflorin on long-term survival rate, nervous system function, body weight and brain neurons in rats were observed. Results The nicotiflorin had significantly improved the long-term survival rate of cerebral ischemia rats, which also promoted weight gain, alleviated pathological damage of brain tissue, maintained morphology of brain neurons and function of nervous system. Conclusion The nicotiflorin has obvious long-term protective effect on ischemic stroke rats and the mechanism may be related to the protection of the structure and function of brain neurons. |
| keywords:nicotiflorin ischemic stroke neuroprotection pathology |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
| 关闭 |
|
|
|
