| 基于前置审核系统优化的三唑类抗真菌药与他汀类药物相互作用精细化审核 |
| 投稿时间：2021-09-27 修订日期：2022-01-29 点此下载全文 |
| 引用本文：刘胜,陈敏,凃远珍.基于前置审核系统优化的三唑类抗真菌药与他汀类药物相互作用精细化审核[J].药学实践杂志,2022,40(2):175~179 |
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| 基金项目:四川省绵阳市2020年科研课题（202066） |
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| 中文摘要:目的 为更好开展三唑类抗真菌药与他汀类药物相互作用审核，保障患者用药安全，提升药师人工审核效率。方法 通过整理汇总三唑类抗真菌药与他汀类药物相互作用信息，得到这两类药物间相互作用较小的优势搭配。同时，优化药物相互作用全人工审核的流程，并在系统的医生端预先设置好这两类药物的优势搭配，医生开具的处方或医嘱用药有明显相互作用时，医生可根据信息系统提示及时调整药物。结果 优化后，大多数医生根据系统提示优先选择这两类药物相互作用较小的搭配，药师人工审核时发现有明显相互作用的药物合用次数显著减少（P<0.05），审核效率得到提升，降低了因药物相互作用带给患者的用药安全风险。结论 基于前置审核系统优化的三唑类抗真菌药与他汀类药物相互作用精细化审核，在提升患者用药安全和药师人工审核效率方面具有积极作用。 |
| 中文关键词:前置审方系统 三唑类抗真菌药 他汀类药物 相互作用 精细化审核 |
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| Refinement review of the interactions between triazole antifungal agents and statins based on the optimization of the pre-prescription audit system |
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| Abstract:Objective To better carries out the review of the interaction between triazole antifungal drugs and statins, ensure drug safety for patients and improve the efficiency of the manual review of pharmacists. Methods The advantageous combination with less interaction between the two kinds of drug was obtained by summarizing the interaction information of triazole antifungal drugs and statins. At the same time, optimizing the process of full manual reviews for drug interaction, and the advantageous combination of the two kinds of drug will be set up in advance on the doctor side of the review system. Doctors can adjust the drug in time according to the prompts of the information system when there is a significant interaction of the two kinds of drug in the prescription or medical order, which is issued by the doctors. Results After optimization, most doctors choose the drug combination of less interaction between the two kinds of drug according to the system prompts. The number of drug combinations of significant interaction which is manually reviewed by pharmacists is significantly reduced (P<0.05), and the review efficiency is improved, the drug safety risks brought by drug interactions to patients are reduced. Conclusion Refinement review of drug interactions between triazole antifungal agents and statins based on the optimization of the pre-audit system plays a positive role in improving the safety of patients’ medication and the efficiency of pharmacists' manual auditing. |
| keywords:pre-prescription review system triazole antifungal agents statins interactions refined review |
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