| 黄芩素抗肿瘤作用及其机制研究新进展 |
| 投稿时间：2020-04-06 修订日期：2020-06-03 点此下载全文 |
| 引用本文：董家潇,金永生,曹莺.黄芩素抗肿瘤作用及其机制研究新进展[J].药学实践杂志,2021,39(1):9~12,43 |
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| 中文摘要:黄芩素（baicalein, BE）是来源于黄芩干燥根中的有效成分，在结构上属于多羟基黄酮类化合物，具有多种药理活性。其中，黄芩素的抗肿瘤作用受到广泛的关注，它可以通过诱导肿瘤细胞凋亡和侵袭，抑制肿瘤血管生成，清除自由基等来发挥抗肿瘤作用。结合近年来国内外研究现状，对黄芩素在其抗肿瘤作用及其机制研究作一综述，为寻找开发潜在的新型抗肿瘤药物提供理论依据。 |
| 中文关键词:黄芩素 抗肿瘤 机制 |
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| New advances in baicalein's antitumor effects and mechanisms |
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| Abstract:Baicalein (BE) is an active ingredient derived from the root of Scutellaria baicalensis Georgi. It is a polyhydroxyflavonoid in structure and has many biological activities. Among them, the antitumor effects of baicalein have received widespread attention. It exerts anti-tumor effects by inducing tumor cell apoptosis and invasion, inhibiting tumor angiogenesis, and eliminating free radicals. This article reviews the most recent research works of baicalein in its anti-tumor effects and mechanisms. It is aimed to provide a theoretical basis for the search and development of potential new anti-tumor drugs. |
| keywords:baicalein anti-tumor mechanism |
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