| 2018版基本药物目录剂型规格分析——以电解质和解热镇痛药为例 |
| 投稿时间：2020-03-31 修订日期：2020-06-02 点此下载全文 |
| 引用本文：张涛志,王艳文,李萌,尹续续,刘伟.2018版基本药物目录剂型规格分析——以电解质和解热镇痛药为例[J].药学实践杂志,2020,38(6):568~573 |
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| 中文摘要:目的 为完善我国基本药物目录中电解质和解热镇痛药收录药品剂型和规格的遴选标准提供数据参考，以提高该部分药品对儿童的适用性及基本药物的可及性。方法 通过系统检索电解质及解热镇痛药相关药品上市及价格情况，使用Excel软件对数据进行处理，对不同剂型规格进行对比和分析。结果 水、电解质及酸碱平衡药共收录8个品种，镇痛、解热、抗炎、抗风湿、抗痛风药共收录16个品种。该部分基药的剂型和规格大多具有批准文号数多、医药采购平台挂网企业多且考虑儿童用药所需的特点，同时这些药品也考虑到了不同剂型、规格之间价格的适宜性，但氯化钾注射液、葡萄糖注射液和对乙酰氨基酚所收录的剂型和规格还有待完善。结论 基药目录收录药品剂型及规格的遴选应从基药的批准文号数、各省医药采购平台挂网企业数及价格和特殊人群的临床需要综合评价，建议将10 ml:1 g氯化钾注射液、50 ml葡萄糖注射液、对乙酰氨基酚栓剂及滴剂纳入基药目录。 |
| 中文关键词:基本药物目录 剂型规格 电解质 解热镇痛药 |
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| Dosage form and specification analysis on electrolytes and antipyretic analgesics in 2018 National Essential Medicines List |
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| Abstract:Objective To provide data reference for improving the selection criteria of the dosage forms and specifications of the electrolytes and antipyretic analgesics in the Essential Medicines List, and to improve the applicability of these medicines to children and the availability of essential medicines.Methods The market and prices of electrolytes and antipyretic analgesics were retrieved by the system. The data were processed by Excel software, and the different dosage forms were compared and analyzed.Results 8 medication classes were included for adjusting water, electrolytes and acid-base balance, and another 16 classes were analgesic, antipyretic, anti-inflammatory, anti-rheumatic and anti-gout drugs. Those medications were characterized with many registered approval numbers, manufacturers and some considerations for pediatric uses. The proper prices were given for different dosage forms and specifications. There is a room for improvement regarding the specifications of potassium, glucose injections, and acetaminophen preparations.Conclusion The selection of pharmaceutical dosage forms and specifications in the Essential Medicines List should be comprehensively evaluated from the registered approval numbers of base medicines, the manufacturers and related prices in pharmaceutical procurement platforms from various provinces, and the clinical needs for special populations. It is recommended that 10 ml: 1 g potassium chloride injection, 50 ml glucose injection，acetaminophen suppositories and drops were included in the Essential Medicines List. |
| keywords:Essential Medicines List dosage form and specification electrolytes antipyretic analgesics |
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