啤酒花抗骨质疏松的应用及展望
投稿时间:2020-07-16  修订日期:2020-08-31  点此下载全文
引用本文:刘晓燕,夏天爽,董志敏,蒋益萍,秦路平,辛海量.啤酒花抗骨质疏松的应用及展望[J].药学实践杂志,2020,38(6):492~495
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作者单位E-mail
刘晓燕 海军军医大学药学院上海 200433  
夏天爽 海军军医大学药学院上海 200433  
董志敏 海军军医大学药学院上海 200433
上海师范大学生命科学学院上海 200234 
 
蒋益萍 海军军医大学药学院上海 200433  
秦路平 海军军医大学药学院上海 200433
浙江中医药大学药学院浙江 杭州 310053 
 
辛海量 海军军医大学药学院上海 200433 hailiangxin@163.com 
基金项目:国家自然科学基金(U1603283)
中文摘要:啤酒花是我国新疆药食兼用的特色资源植物。除广泛用于啤酒酿制外,人们很早就认识到啤酒花的药用价值,尤其是将其用于绝经后骨质疏松的治疗。现代药理研究发现,啤酒花的多种活性成分在抗骨质疏松药物研发方面具有巨大潜力。然而,近年来,我国野生啤酒花资源品种退化严重,活性成分含量差异较大。保障优良的啤酒花种质资源,是啤酒花开发利用的前提。本文就啤酒花的主要化学成分及其防治骨质疏松症的作用及相关应用进行综述,并就目前存在的问题进行探讨,旨在为啤酒花抗骨质疏松的开发利用提供借鉴。
中文关键词:啤酒花  化学成分  骨质疏松症
 
Application and prospect of Humulus lupulus L. in anti-osteoporosis
Abstract:Humulus lupulus is a kind of special resource plant used both as medicine and food in Xinjiang. In addition to being widely used in beer brewing, Humulus lupulus has long been recognized for its medicinal value, especially for the treatment of postmenopausal osteoporosis. Modern pharmacological research shows that its active components have great potential in the development of anti-osteoporosis drugs. However, in recent years, the wild Humulus lupulus resources in China have been seriously degraded, and the contents of active components are quite different. Ensuring high-quality Humulus lupulus germplasm resources is a prerequisite for the development and utilization of Humulus lupulus. This paper reviews the major chemical components of Humulus lupulus and their effects and application in the prevention and treatment of osteoporosis, and discusses the existing problems, aiming to provide a reference for the development and utilization of Humulus lupulus against osteoporosis.
keywords:Humulus lupulus  chemical constituents  osteoporosis
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