| 风寒湿灵散质量标准研究 |
| 投稿时间：2017-11-28 修订日期：2018-01-09 点此下载全文 |
| 引用本文：曹红,单婷婷,胡丹,张贵英.风寒湿灵散质量标准研究[J].药学实践杂志,2018,36(4):343~346 |
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| 基金项目:全军医疗机构制剂标准提高重点课题（13ZJZ16） |
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| 中文摘要:目的 修订风寒湿灵散的质量控制方法。方法 采用薄层色谱（TLC）法对处方中狼毒、白芷、三七、赤芍、姜黄等药材进行定性鉴别；采用HPLC法测定处方中欧前胡素的含量。结果 在TLC色谱中，可鉴别制剂中的狼毒、白芷、三七、赤芍、姜黄；欧前胡素在0.033 6~0.269 0 μg范围内呈良好的线性关系，r值为0.999 9；样品中欧前胡素的平均加样回收率为96.77%（RSD为1.63%）。结论 此方法简便、准确性好，为控制风寒湿灵散的质量提供了科学依据。 |
| 中文关键词:高效液相色谱 薄层色谱 风寒湿灵散 欧前胡素 |
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| Study on the quality standard for Fenghan Shiling San |
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| Abstract:Objective To revise and improve the quality standard for Fenghan Shiling San. Methods The thin layer chromatography was used to identify euphorbiae ebracteolatae radix, angelicae dahuricae radix, notoginseng radix et rhizome, radix paeoniae rubra and rhizoma curcumae longae. The high-performance liquid chromatography was applied to determine the contents of imperatorin in Fenghan Shiling San. Results Euphorbiae ebracteolatae radix, angelicae dahuricae radix, notoginseng radix et rhizome, radix paeoniae rubra and rhizoma curcumae longae can be identified by TLC. Imperatorin showed a good linear relationship in a range of 0.033 6-0.269 0 μg, r=0.999 9. The average recovery of imperatorin was 96.77%(RSD=1.63%, n=6). Conclusion This accurate and quick method can be used for the quality control of Fenghan Shiling San. |
| keywords:HPLC TLC Fenghan Shiling San imperatorin |
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