| 盐酸美金刚治疗缺血性脑卒中研究进展 |
| 投稿时间：2018-05-23 修订日期：2018-06-25 点此下载全文 |
| 引用本文：杨世畅,李雪梅,王曙霞,何荆贵.盐酸美金刚治疗缺血性脑卒中研究进展[J].药学实践杂志,2018,36(4):293~296 |
| 摘要点击次数: 1517 |
| 全文下载次数: 1846 |
|
| 基金项目:解放军总医院扶持基金（2016FC-CXYY-1009） |
|
| 中文摘要:缺血性脑卒中是临床高发病，也是造成老年人永久残疾的重要原因之一。目前存在的治疗方法窗口期较短，寻找一种有效治疗缺血性脑卒中的药物是近年来研究的重点。盐酸美金刚是N-甲基-D-天冬氨酸受体拮抗剂，可有效缓解阿尔兹海默病的病程，近年来相关研究显示，盐酸美金刚可能具有治疗缺血性脑卒中的作用，综述该方面的研究进展，为相关药物的开发和治疗提供参考。 |
| 中文关键词:缺血性脑卒中 盐酸美金刚 N-甲基-D-天冬氨酸受体拮抗剂 |
| |
| Progress in the ischemic stroke treatment with memantine hydrochloride |
|
|
| Abstract:Ischemic stroke is one of the leading causes of permanent disability in the elderly with high prevalence rate. The therapy window of current treatment is relatively short. Finding an effective treatment for ischemic stroke is the key point of research work. Memantine hydrochloride is an N-methyl-D-aspartate receptor antagonist which could effectively alleviate the course of Alzheimer's disease. Recent studies have shown that memantine may play a role in the treatment of ischemic stroke. Related literatures were reviewed, hoping to provide new ideas for the protective mechanism of memantinein the treatment of ischemic stroke. |
| keywords:ischemic stroke memantine hydrochloride N-methyl-D-aspartate receptor antagonist |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
| 关闭 |
