| 芪黄扶正颗粒的质量控制方法研究 |
| 投稿时间：2017-03-03 修订日期：2017-06-30 点此下载全文 |
| 引用本文：曾令军,宋洪涛,冯英力,程惠华.芪黄扶正颗粒的质量控制方法研究[J].药学实践杂志,2017,35(6):530~534 |
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| 基金项目:福建中医药大学临床专项校管课题（XB2016078） |
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| 中文摘要:目的 建立芪黄扶正颗粒的质量控制方法。方法 采用TLC法对方中黄芪、熟地黄、山茱萸、当归、川芎、赤芍、牡丹皮、麦门冬进行定性鉴别；采用HPLC法对臣药山茱萸中马钱苷进行含量测定。结果 建立了主要药味的TLC鉴别方法，斑点清晰，阴性无干扰；马钱苷在4.02~80.40 μg/ml范围内线性关系良好（r=0.999 9），平均加样回收率为99.02%，RSD为0.64%（n=9）。结论 本研究建立的质量控制方法准确、可靠、专属性强，为芪黄扶正颗粒的质量控制奠定了基础。 |
| 中文关键词:芪黄扶正颗粒 质量控制 马钱苷 |
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| Quality control methods for Qihuang Fuzheng particle |
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| Abstract:Objective To establish the quality control methods for Qihuang Fuzheng particle.Methods Astragali Radix, Rehmanniae Radix Praeparata, Corni Fructus, Chuanxiong Rhizoma, Angelicae Sinensis Radix, Paeoniae Radix Rubra, Moutan Cortex, and Ophiopogonis Radix were identified with TLC. HPLC method was used for loganin assay in Corni Fructus.Results TLC identification methods for the main components were established. The TLC spots were clear with good separation. No interference was detected from the negative samples. The peak response and concentration of loganin showed good linear relationship over the range of 4.02-80.40 μg/ml (r=0.999 9). The mean recovery of loganin was 99.02%(RSD=0.64%, n=9). Conclusion The established quality control methods are accurate, reliable, and specific, which lay a foundation for the quality control of Qihuang Fuzheng particle. |
| keywords:Qihuang Fuzheng particle quality control loganin |
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