| 两面针碱全合成及活性研究进展 |
| 投稿时间：2016-03-07 修订日期：2016-12-22 点此下载全文 |
| 引用本文：赵增,陈浩,杨鸟,孙青龑,柳润辉.两面针碱全合成及活性研究进展[J].药学实践杂志,2017,35(2):102~107,149 |
| 摘要点击次数: 1322 |
| 全文下载次数: 1193 |
|
|
| 中文摘要:两面针碱是传统中药两面针根的提取物，属于苯并菲啶类生物碱。研究发现两面针碱具有多种生物活性，对肿瘤、疟疾等多种疾病有效。笔者对两面针碱全合成方法及近年来的活性研究进行综述。 |
| 中文关键词:两面针碱 全合成 生物活性 作用机制 |
| |
| Research progress on total synthesis and activity of nitidine |
|
|
| Abstract:Nitidine is a benzophenanthridine alkaloid derived from Zanthorulum nitidum (Roxb.) DC root. Research shows that nitidine displays rich biological activities, such as anti-tumor, anti-inflammatory, anti-malaria and etc. This paper reviewed the progress of the total synthesis methods for nitidine and recent research on bioactivities. |
| keywords:nitidine total synthesis bioactivity mechanism of action |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
| 关闭 |
|
|
|
