| 纳米载药系统逆转肿瘤及骨肉瘤多药耐药的研究进展 |
| 投稿时间：2014-12-21 修订日期：2015-05-06 点此下载全文 |
| 引用本文：陈自强,张玮,李玉平,王晓宇.纳米载药系统逆转肿瘤及骨肉瘤多药耐药的研究进展[J].药学实践杂志,2016,34(2):103~105 |
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| 中文摘要:多药耐药是肿瘤化疗中的重要难题,多药耐药的机制复杂,目前尚无有效的治疗策略。纳米载药系统具有靶向性、载药种类多样等优点,近年来成为对抗肿瘤多药耐药的递药载体的重要研究方向。对肿瘤抑制的不同机制进行讨论,并对纳米载药系统逆转骨肉瘤多药耐药的研究进展进行综述。 |
| 中文关键词:肿瘤 骨肉瘤 多药耐药 纳米载药系统 |
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| Progress on nano-sized drug delivery system reversing tumor and multidrug resistance of osteosarcoma |
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| Abstract:Multidrug resistance(MDR) of tumor cell is the major problem for chemotherapy. However, there is no effective strategy to overcome MDR due to the complicated mechanism. The nano-sized drug delivery system could target to the tumor cell. Moreover, it could delivery different kinds of drugs. Therefore, the nano-sized drug delivery system has become a promising approach to reverse MDR. The nano-sized drug delivery system which is applied to treat the MDR of tumor(osteosarcoma) was summarized and the reverse mechanism was discussed. |
| keywords:tumor osteosarcoma MDR nano-sized drug delivery system |
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