丹参素及其衍生物心血管作用机制的研究进展 |
投稿时间:2013-12-23 修订日期:2014-04-18 点此下载全文 |
引用本文:焦育强,刘文斌,袁夏,姜玉,田霖,金磊,张川.丹参素及其衍生物心血管作用机制的研究进展[J].药学实践杂志,2015,33(5):389~391,405 |
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中文摘要:丹参素是丹参的主要水溶性活性成分之一,具有多种药理活性,尤其对心血管系统具有明显的保护作用。笔者从抗凋亡、抗氧化、抑制钙超载和作用于炎症反应通路等方面,对丹参素及其衍生物心血管药理作用机制进行综述。 |
中文关键词:丹参素 丹参素衍生物 抗凋亡 抗氧化 钙超载 炎症反应 |
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Study progress of Danshensu and its derivatives in cardiovascular mechanism |
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Abstract:Danshensu is one of the main water soluble active ingredients of Salvia miltiorrhiza, which has many pharmacological activities, especially in cardiovascular system. The cardiovascular pharmacological mechanism of Danshensu and its derivatives from the view of anti-apoptosis, antioxidant, inhibiting calcium overload and role in the inflammatory reaction pathways etc. were summarized in this article. |
keywords:Danshensu derivatives anti-apoptosis antioxidant calcium overload inflammatory reaction |
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