| 2种保肝方案在肝硬化失代偿期治疗中的药物经济学评价 |
| 投稿时间：2013-08-30 修订日期：2014-04-14 点此下载全文 |
| 引用本文：孙滢,王静雯,史国兵.2种保肝方案在肝硬化失代偿期治疗中的药物经济学评价[J].药学实践杂志,2015,33(1):80~82 |
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| 中文摘要:目的 运用药物经济学原理和方法对两种保肝治疗方案进行成本-效果分析,为肝硬化失代偿期的患者选择较优的治疗方案提供依据。方法 选择2010-2012年入院,诊断为肝硬化失代偿期,符合Chlid-Pugh分级为B~C级的患者。将入选患者分为A、B、C 3组,分别应用复方二氯醋酸二异丙胺注射液、多烯磷脂酰胆碱注射液、复方二氯醋酸二异丙胺注射液联合多烯磷脂酰胆碱注射液进行保肝治疗,但由于A组的Child-Pugh分级所占比例与B组、C组存在统计学差异,排除A组,只观察B、C两组的疗效,并进行成本-效果分析。结果 B、C两组的治疗时间分别为(15.5±8.55) d和(12.13±7.61) d;总有效率分别为50%和60%,差异无统计学意义(P>0.05)。而两组的总成本分别为(1 640.52±905.26) 元和(2 576.51±1 615.99) 元,有显著性差异。结论 B组方案较佳。 |
| 中文关键词:肝硬化 失代偿期 药物经济学 成本-效果分析 保肝方案 |
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| Pharmacoeconomics analysis of two treatment schemes in decompensated cirrhosis patients |
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| Abstract:Objective To evaluate two treatment schemes of liver protection and choose the optimal radiotherapy using pharmacoeconomics principle and methods. Methods In-patients who were diagnosed as decompensated cirrhosis patients and simultaneously conformed to the Chlid-Pugh graduation of level B-C during 2010-2012 were chosen.The chosen patients were divided into A,B and C group separately,and were treated with the compound prescription of dichloro acetic acid two isopropyl amine inoculation fluid,the polyene phosphatide acid radical choline inoculation fluid,and the compound prescription dichloro acetic acid two isopropyl amine inoculation fluid and the polyene phosphatide acid radical choline inoculation fluid.Cost effectiveness analysis was done between group B and C. Results Treatment time of group B and C was (15.5±8.55) d and (12.13±7.61) d respectively.The total effectiveness was 50% and 60% respectively and the difference was with non-statistics significance (P>0.05).The total cost was (1 640.52±905.26) yuan and (2 576.51±1 615.99) yuan respectively. Conclusion Group B was the better treatment scheme. |
| keywords:cirrhosis decompensated period drug economics cost-effectiveness analysis protect liver scheme |
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