| 色谱-质谱联用技术测定人体内类固醇激素的研究进展 |
| 投稿时间：2013-08-28 修订日期：2014-01-14 点此下载全文 |
| 引用本文：钱跹,赵亮,吕磊,张海,李悦悦,张国庆.色谱-质谱联用技术测定人体内类固醇激素的研究进展[J].药学实践杂志,2014,32(3):176~180,190 |
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| 中文摘要:类固醇激素是高效能的生物化学物质,在多种生理活动中发挥显著的调节作用,但在体内的含量极低,因此对其进行准确定量具有重要意义。在各种检测方法中,色谱-质谱联用技术因具有高效、快速、灵敏的优点而得以广泛应用。笔者综述近年来色谱-质谱联用技术在内源性类固醇激素测定中的应用,为进一步的临床研究提供参考依据。 |
| 中文关键词:类固醇激素 含量测定 色谱-质谱联用 研究进展 |
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| Research progress in steroid hormone analysis in vivo by chromatography-mass spectrometry |
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| Abstract:Steroid hormones were chemical compounds of high efficiency, which played a significant role in various physiological activities. However, the concentrations of hormones in vivo were extremely low, so it was very important for their accurate quantification. Chromatography-mass spectrometry technology was widely employed because of advances in high efficient, rapid and sensitive. The application of steroid hormone analysis by chromatography-mass spectrometry was reviewed in this paper, which could provide reference for furthuer clinical research. |
| keywords:steroid hormone determination chromatography-mass spectrometry review |
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