| 五酯片治疗酒精性肝炎的疗效观察 |
| 投稿时间：2013-01-07 修订日期：2013-05-30 点此下载全文 |
| 引用本文：王国平,张忠臣,夏晨梅.五酯片治疗酒精性肝炎的疗效观察[J].药学实践杂志,2013,31(6):467~469 |
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| 中文摘要:目的 观察五酯片治疗酒精性肝炎的疗效。方法 将符合纳入标准的110名患者随机分成试验组和对照组。试验组使用五酯片;对照组使用甘草酸二铵肠溶胶囊。观察两组治疗前后临床疗效及谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆红素(TBIL)、γ-谷氨酰转肽酶(γ-GT)的差别。结果 ①试验组总有效率(92.86%)显著高于对照组(77.78%),差异有统计学意义(P<0.05);②两组治疗后ALT、AST、TBIL、γ-GT较治疗前均显著下降,差异均有统计学意义(P<0.01);③治疗后,试验组ALT、AST、TBIL、γ-GT显著低于对照组,差异均有统计学意义(P<0.01)。结论 五酯片可提高酒精性肝炎临床疗效,改善肝功能。 |
| 中文关键词:酒精性肝炎 五酯片 肝功能 |
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| The clinical observation of Wuzhi Pian in treatment of alcoholic hepatitis |
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| Abstract:Objective To explore the efficacy of WuzhiPian in the treatment of alcoholic Hepatitis. Methods 110 patients with alcoholic hepatitis were randomly divided into the observed group(accepted treatment of WuzhiPian) and the control group(accepted treatment of Diammonium glycyrrhizinate enteric-coated capsules). The difference of clinical efficacy and alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), gamma glutamyl transpeptidase (γ-GT) were compared between the two groups. Results The effective rate in the observed group(92.86%) was significantly higher than that in the control group(77.78%)(P<0.05); ② The concentration of ALT, AST, TBIL andγ-GT after treatment were significantly lower than that before the treatment(P<0.01); ③After treatment, the concentration of ALT, AST, TBIL andγ-GT in the observed group were significantly lower than that in the control group(P<0.01). Conclusion WuzhiPian could increase therapeutic effect and improve liver function in alcoholic hepatitis patients. |
| keywords:alcoholic hepatitis Wuzhi Pian liver function |
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