| 治疗痛风药物研究进展 |
| 投稿时间：2012-02-09 修订日期：2012-05-21 点此下载全文 |
| 引用本文：徐娜,陈海生.治疗痛风药物研究进展[J].药学实践杂志,2013,31(1):14~18 |
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| 基金项目:上海市中药现代化专项资助(09dZ1974000);上海市重点学科建设项目(B906). |
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| 中文摘要:随着人们生活水平的提高, 痛风的发病率不断上升并出现低龄化, 寻找高效低毒的抗痛风药物成为当务之急。目前,对于痛风的常规治疗仍以西药为主,这些药物以不同的作用机制达到缓解或治疗痛风的目的,但临床发现它们都具有一定的毒副作用。近年来,越来越多的研究者着手于抗痛风天然药物的开发,其疗效与毒副作用尚待进一步的临床验证。本文对目前临床上常用的抗痛风药物及正在研发中的抗痛风药物进行了综述,总结痛风病不同分期的药物治疗特点,阐述各期药物治疗潜在危害和处理方法,归纳抗高尿酸血症或痛风的中药研究,为开发新型抗痛风药物提供有效途径,并对抗痛风新药的研发进行了展望。 |
| 中文关键词:痛风 抗痛风药 治疗进展 中药 |
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| Advance in drug therapy of gout |
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| Abstract:With the development of the living standard, the incidence of gout was rising and the trend of patient age with gout getting younger. Developing high-effective and low-adverse anti-gout drugs was a priority of the research agenda. At present, conventional therapies of gout lean on western medicines. These drugs relieved or treated gout with different mechanisms, but all of them had different side-effects. Recently, more and more researchers started to develop traditional Chinese medicine to treat gout and their effectiveness and the side-effects need further clinical verification. The commonly used anti-gout drugs or new drugs under research including their treatment characteristics, potential hazards and their therapeutic principles at different clinical stages were summarized in this article, especially in some anti-hyperuricemia or anti-gout Chinese Medicine, which gave an effective way to develop new anti-gout drugs. |
| keywords:gout anti-gout drugs advance therapeutics Chinese Medicine |
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