| 纳米结构脂质载体用于难溶性药物口服传递的研究进展 |
| 投稿时间：2012-04-21 修订日期：2012-05-29 点此下载全文 |
| 引用本文：温许,胡雄伟,吴昊,宋洪涛.纳米结构脂质载体用于难溶性药物口服传递的研究进展[J].药学实践杂志,2012,30(4):254~257,301 |
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| 中文摘要:纳米结构脂质载体可以提高难溶性药物的口服生物利用度,是一种具有前景的难溶性药物口服传递系统.通过查阅文献,对纳米结构脂质载体常见的制备材料、方法,体外表征和释药,及提高难溶性药物口服生物利用度的机制进行综述. |
| 中文关键词:纳米结构脂质载体 制备方法 体外表征 难溶性药物 |
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| Progress on nanostructured lipid carriers as oral poorly soluble drugs delivery systems |
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| Abstract:Nanostructured lipid carrier,which could enhance the bioavailability of poorly soluble drugs,was a kind of promisingoral delivery systems for insoluble drugs.The preparation,characterization, drug release in vitro and the mechanism of NLC for enhancing the bioavailability of poorly soluble were reviewed in this paper. |
| keywords:nanostructured lipid carrier method preparation characterization poorly soluble drugs |
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