| 抗肝纤维化的中药有效成分及其作用机制研究进展 |
| 投稿时间：2011-09-02 修订日期：2011-12-21 点此下载全文 |
| 引用本文：孙蕾,邓华平,席忠新,李霞,孙连娜.抗肝纤维化的中药有效成分及其作用机制研究进展[J].药学实践杂志,2012,30(2):92~95,127 |
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| 基金项目:国家重大新药创制专项(2009ZX09502-021). |
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| 中文摘要:肝纤维化是多数慢性肝病所共有的病理特征,肝纤维化逐步发展形成肝硬化,最终导致肝癌。本文将近年报道的具有抗HF作用的中药有效成分作简单综述,归纳为黄酮类、生物碱类、萜类、酚类化合物,并总结了各类有效成分抗HF的作用机制,为深入开展中药抗HF的研究提供一定的参考。 |
| 中文关键词:抗肝纤维化 中药有效成分 作用机制 |
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| Advances in active ingredients and action mechanism of TCM in treatment of hepatic fibrosis |
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| Abstract:Hepatic fibrosis was the common feature of pathology in almost all patients with chronic liver injury, which led to cirrhosis gradually and liver cancer ultimately. The anti-hepatic fibrosis active ingredients from TCM, including flavones, alkaloids, terpenes and phenols compounds were reviewed with the action mechanism in this paper, which could provide some references for the further study about the anti-hepatic fibrosis of TCM. |
| keywords:hepatic fibrosis active ingredients of TCM action mechanism |
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