银杏叶中萜内酯类化合物的研究进展 |
投稿时间:2011-05-11 修订日期:2011-06-21 点此下载全文 |
引用本文:刘彬果,张新萍,刘岩.银杏叶中萜内酯类化合物的研究进展[J].药学实践杂志,2011,29(6):421~425 |
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中文摘要:银杏萜内酯是银杏叶提取物及其制剂中的主要活性成分,是公认的血小板激活因子拮抗剂,被广泛用于心脑血管疾病。本文对银杏叶中萜内酯类化合物的化学成分、提取分离、含量检测及药理作用方面的研究进展进行了综述,并对其研究前景进行了展望。 |
中文关键词:银杏叶萜内酯 化学成分 提取 血小板活化因子 |
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Advances in terpene trilactones of Ginkgo leaves |
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Abstract:Of all the compound classes present in G. biloba, the terpene trilactones had received the most attention. The ginkgolides and bilobalide were selective platelet-activating factor antagonists and widely applied in the illness of blood vessel of heart and brain. Studies on the chemical constituents, extraction and separation, the determination of content and the pharmacological activity about terpene trilactones of Ginkgo leaves were summarized and the study prospect were made. |
keywords:terpene trilactones chemical constituents extraction platelet-activat-ing factor |
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