瑞香狼毒提取物尼地吗啉的抗肿瘤研究概况
投稿时间:2010-11-05  修订日期:2011-04-29  点此下载全文
引用本文:王园园,王鑫,王义善.瑞香狼毒提取物尼地吗啉的抗肿瘤研究概况[J].药学实践杂志,2011,29(5):328~330,335
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作者单位E-mail
王园园 解放军第107医院国家中西医结合肿瘤治疗重点专科,山东 烟台 264002  
王鑫 解放军第107医院国家中西医结合肿瘤治疗重点专科,山东 烟台 264002  
王义善 解放军第107医院国家中西医结合肿瘤治疗重点专科,山东 烟台 264002 wys@107zlzx.com 
基金项目:全军科技攻关项目(06G034).
中文摘要:本文就瑞香狼毒中抗肿瘤活性成分尼地吗啉的抗肿瘤机制、研究现状及其临床应用存在的问题进行了较完整的总结和介绍,进一步分析了尼地吗啉作为一种抗癌药物的可行性及临床应用减毒增效方案,籍此为尽可能的发挥祖国传统肿瘤中医中药巨大潜能,深入研究抗肿瘤有效单体成分提供参考。
中文关键词:瑞香狼毒  尼地吗啉  中药单体  抗肿瘤
 
Progress on diterpenoids gnidimacrin in Stellera chamaejasma L.
Abstract:A relatively complete summary on the anti-tumor component gnidimacrin was introduced, which was extracted from Stellera chamaejasma L. The research status of gnidimacrin's antitumor mechanism and its clinical application were reviewed. A further analysis on the feasibility and attenuated efficiency programs of the Gnidimacrin as an antitumor drug was made. The review could provide reference to exert the enormous potential of Chinese traditional medicine as much as possible and to deeply excavate the effective monomers.
keywords:Stellera chamaejasma L.  gnidimacrin  chinese medicine  antitumor
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