| 口服缓控释微丸的研究进展 |
| 投稿时间：2010-09-15 修订日期：2010-12-21 点此下载全文 |
| 引用本文：陈婷,张倩,宋洪涛.口服缓控释微丸的研究进展[J].药学实践杂志,2011,29(3):169~172,192 |
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| 中文摘要:目的 综述近年来国内外缓控释微丸的研究进展,并展望微丸制剂的发展前景。 方法 查阅相关文献,并将其分析、归纳。 结果 阐明了不同种类缓控释微丸的特点、所选用的辅料、制备工艺及微丸压片技术。 结论 微丸作为一种多单元释药系统,具有较多优点,随着现代制备工艺的逐渐成熟及辅料的发展,微丸成为目前缓控释制剂发展的重要方向。 |
| 中文关键词:微丸 辅料 包衣 压片技术 |
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| Progress of oral sustained-release and controlled-release pellets |
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| Abstract:Objective To summarize the recent advances in oral sustained/controlled release pellets in international and domestic and prospect its developing future. Methods A great quantity of references were comprehensively reviewed. Results Various kinds of information of oral sustained/controlled release pellets including the characteristic,excipients,preparation methods and squash technique were summarized. Conclusions Pellets as multiple-unit drug delivery system have many advantages.With preparation techniques and excipient materials were gradually developed,pellets would play an important part in the development of sustained/controlled release drug delivery system. |
| keywords:pellets excipient coating squash technique |
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