2009年我院87例药品不良反应分析
投稿时间:2010-03-04  修订日期:2010-03-24  点此下载全文
引用本文:马明华,余自成,邱瑾,傅喆暾.2009年我院87例药品不良反应分析[J].药学实践杂志,2010,28(4):313~315
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作者单位
马明华 上海市杨浦区中心医院药剂科,上海200090 
余自成 上海市杨浦区中心医院药剂科,上海200090 
邱瑾 上海市杨浦区中心医院药剂科,上海200090 
傅喆暾 上海市杨浦区中心医院药剂科,上海200090 
中文摘要:目的:总结我院2009年药品不良反应(ADR)监测情况,促进临床安全、合理用药。方法:采用描述性研究方法,对我院2009年上报的87例疑似药品不良反应,分别从患者的一般情况,药物种类、用药途径、临床表现等方面进行统计、分析与评价。结果:87例药品不良反应监测报告中,涉及51种药品,由抗菌药物引起的疑似药品不良反应最多,共54例(占62.07%);由中药制剂引起的疑似药品不良反应其次,有6例(占6.90%);由静脉滴注用药途径引起疑似药品不良反应最多见,有61例(占70.11%);发生ADR的患者中女性多于男性(1:0.64),65岁以上患者发生ADR多于其他年龄段;ADR的临床表现以皮肤及其附件损害最多见,占57.47%。结论:我院抗菌药物静脉注射引发的不良反应较多,应予以特别关注。
中文关键词:药品不良反应  抗菌药物
 
Analysis of 87 ADR cases in our hospital in 2009
Abstract:ObjectiveTo enhance the level of safe and rational use of drugs throgh investigating the adverse drug reactions(ADR) cases in our hospital in 2009.Methods 87 ADR cases in our hospital in 2009 were collected which were analyzed according to the patient's age and sex,drug species,route of administration and clinical manifestation etc.Results 51 drug species were involved in 87 ADR cases.54 cases(62.07%)were related to antibacterial agents;6 cases(6.90%) were related to the Chinese herba preparation.61cases(70.11%) were induced by intravenous infusion;the ADR cases of female were more than male with the proportion of 1:0.64;the ADR cases occurred in patients older than 65 years were more than in other age groups;and 57.47% of clinical manifested were skin lesions and accessories injuries.Conclusion The most ADR cases were caused by antibacterial agents through intravenous infusion,which should be taken seriously.
keywords:adverse drug reaction  antibacterial agents
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