替硝唑注射液与3种头孢菌素的配伍稳定性考察
投稿时间:2008-03-28    点此下载全文
引用本文:钱琳.替硝唑注射液与3种头孢菌素的配伍稳定性考察[J].药学实践杂志,2008,(5):367~369,395
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作者单位
钱琳 湖南省人民医院药剂科,湖南长沙410005 
中文摘要:目的:考察25℃、37℃下8 h内替硝唑注射液与注射用头孢硫脒、头孢尼西、头孢他啶配伍的稳定性。方法:采用3种紫外分光光度法测定配伍8 h内替硝唑注射液与3种头孢菌素的含量以判断配伍稳定性。结果:25℃、37℃8 h内3种头孢菌素与替硝唑注射液配伍液含量几乎无改变,紫外曲线未见改变。结论:25℃、37℃8 h内替硝唑注射液可以与上述3种头孢菌素配伍使用。
中文关键词:紫外分光光度法  替硝唑  头孢硫脒  头孢尼西  头孢他啶  配伍稳定性
 
Stability of cephamycins mixed with tinidazole injection
Abstract:Objective:To observe the stability of tinidazole injection mixed with cefathiamidine,cefonicid and ceftazidime injection for 8 hours on 25℃and 37℃,respectively.Methods:The contents of tinidazole injection and three cephamycins were determined by three ultraviolet spectrophotometry methods.Results:After mixed with tinidazole injection for 8 hours,the contents of the three cepha- mycins did not change on 25℃or 37℃.Conclusion:They are all stable for 8 hours on 25℃and 37℃when tinidazole injection is combined with three cephamycins.
keywords:ultraviolet spectrophotometry  tinidazole  cefathiamidine  cefonicid  ceftazidime  compatibility
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