| 复方奥硝唑搽剂的制备与质量控制 |
| 投稿时间：2007-07-09 点此下载全文 |
| 引用本文：邢启德,张志武,李红兵,李国柱.复方奥硝唑搽剂的制备与质量控制[J].药学实践杂志,2008,(3):203~205 |
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| 中文摘要:目的:研制复方奥硝唑搽剂并对其质量进行控制。方法:以奥硝唑和硼酸为主药制备复方搽剂,采用紫外分光光度法和中和法分别直接测定两组分含量,并对该制剂的稳定性进行考察。结果:奥硝唑、硼酸平均回收率分别为99.98%,100.29%,RSD分别为0.49%,0.97%。结论:复方奥硝唑搽剂配方合理、质控方法可行,所得制剂性质稳定,符合中国药典2005年版的规定,可满足临床用药要求。 |
| 中文关键词:奥硝唑 硼酸 搽剂 制备 质量控制 |
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| Preparation and quality control of compound ornidazole liniment |
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| Abstract:Objective: To study the preparotion and quality control of compound ornidazole liniment.Methods:Prepared compound liniments with ornidazole and boric acid as principle agents.The contents of these two qroups were measured respectively.by UV spectrophotometry adn neutralization method.Then the stability of it was examined.Results: The average recoveries of ornidazole and boric were 99.98% and 100.29% with the RSD of 0.49%,0.97%.Conclusion:The compound ornidazole liniment formula was reasonable;the quality control method was viable;the outcoming liniment was stable,and in line with the 2005 version of Chinese Pharmacopoeia.It could meet the clinical requirment. |
| keywords:Puerarin Microemulsion |
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