乳癖消巴布膏的刺激性、过敏性及经皮毒性研究
投稿时间:2007-01-15  修订日期:2006-09-04  点此下载全文
引用本文:王秋菊,吕娟,张予阳,刘晓秋.乳癖消巴布膏的刺激性、过敏性及经皮毒性研究[J].药学实践杂志,2008,(1):31~34
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作者单位E-mail
王秋菊 沈阳药科大学,辽宁沈阳110016 yuyangzhang2003@yahoo.com.cn 
吕娟 沈阳药大药业有限公司,辽宁沈阳110016  
张予阳 沈阳药科大学,辽宁沈阳110016  
刘晓秋 沈阳药科大学,辽宁沈阳110016  
中文摘要:目的:考察乳癖消巴布膏皮肤用药的安全性。方法:用健康家兔分别进行完整与破损皮肤的皮肤刺激性试验;用健康豚鼠进行皮肤过敏试验;用健康大鼠进行慢性经皮毒性试验。结果与结论:乳癖消巴布膏对家兔无皮肤刺激性,对豚鼠无致敏性,对大鼠无经皮毒性。
中文关键词:乳癖消巴布膏  刺激性  致敏性  经皮毒性
 
Study on the irritation,hypersensitiveness and percutaneous toxicity of Rupixiao patch
Abstract:Objective:To study the safety of Rupixiao patch.Methods:Skin irritation tests were carried on the integral and damaged skin of healht rabbits. The skin hypersensitive test and chronic percutaneous toxicity test were carried on guinea pigs and healthy rats.Results and Conclusion: Irritation,hypersensitiveness and toxicity didn't happened on the rabbits, guinea pigs and rats, respectively.
keywords:Rupixiao patch  skin irritation  skin hypersensitiveness  percutaneous toxicity
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