323例药物不良反应报告分析
投稿时间:2006-06-03    点此下载全文
引用本文:恽芸蕾,缪海均,樊成辉,陈万生.323例药物不良反应报告分析[J].药学实践杂志,2007,(4):261~262
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作者单位
恽芸蕾 第二军医大学长征医院药学部,上海200003 
缪海均 第二军医大学长征医院药学部,上海200003 
樊成辉 第二军医大学长征医院药学部,上海200003 
陈万生 第二军医大学长征医院药学部,上海200003 
中文摘要:目的:通过对我院2005年323例药物不良反应(ADR)报表进行统计分析,研究ADR的发生率与患者年龄及用药情况的关系。方法:采用描述性研究方法对ADR报表进行分类。结果:涉及ADR的药物共有194个品种,其中抗感染类药物引起的ADR发生率最高,抗肿瘤药次之。而ADR引发的组织器官损伤最常见于皮肤过敏反应及消化系统症状。结论:应重视安全合理用药,最大限度地减少ADR的重复发生。
中文关键词:药物不良反应  药物不良反应监测  统计分析
 
Analysis of 323 cases of adverse drug reactions reports
Abstract:Objective:To investigate 323 reports of adverse drug reactions(ADRs)in our hospital in 2005,and to analyze the re- lationship between ADRs and age,the used drugs.Methods:The cases of ADR were analyzed by descriptive study.Results:194 kinds of drugs were involved in.Among them,49(25.30%)kinds were antibiotis in the first rank,40(20.60%)kinds were antineo- plastic agents in second rank.ADR showed the lesion of skin and digestive system mostly.Conclusion:Great attention should be paid to the development of ADR so as to reduce the incidence of ADR.
keywords:adverse drug reactions(ADRs)  ADR monitoring  statistical analysis
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