| 胎盘肽注射液的研制及治疗外阴白斑的疗效 |
| 投稿时间：2006-03-27 点此下载全文 |
| 引用本文：佟志清,杨光照,汪宇,宋永波.胎盘肽注射液的研制及治疗外阴白斑的疗效[J].药学实践杂志,2007,(2):91~93 |
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| 中文摘要:目的:研制胎盘肽注射液,并观察其治疗外阴白色病变的疗效。方法:以健康人胎盘为原料,采用冻融和超滤的方法制备了胎盘肽注射液。用福林-酚法测定多肽含量。观察了该注射液对156例外阴白色病变患者的疗效。结果:胎盘肽在20μg/mL至100μg/mL浓度范围内线性关系良好,平均回收率为100．16%,99．25%,98．59%,RSD分别为1．09,0．48,0．50(n=3)。治疗外阴白色病变的总有效率达100%。结论:胎盘肽注射液作为多肽类生化制剂,工艺简便可行,质量可控,临床疗效满意。 |
| 中文关键词:胎盘肽注射液 制备 外阴白色病变 疗效分析 |
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| Preparation and therapeutic effect on white lesion of vulva of placenta polypeptide injection |
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| Abstract:Objective:To prepare the placenta polypeptide injection and establish the standard of quality control and to evaluate the therapeutic effect on white lesion of vulva.Methods:The placenta polypeptide injection was made from healthy human placenta by the method of thaw and ultrafiltration.The content of polypeptide was determined by Lowry-method.Results:The linear relationship of placenta polypeptide was found from 20μg/mL to 100μg/mL.The average recovery of polypeptide was 100.16%,99.25% and 98.59%,respectively.RSD was 1.09,0.48 and 0.50,respectively(n=6).The overall clinical effective rate for white lesion of vulva was 100%.Conclusion:The placenta polypeptide injection is simple in preparation technique and feasible in quality control.No ad-verse drug reactions were found and the clinical effect is satisfactory. |
| keywords:placenta polypeptide injection preparation white lesion of vulva quality control therapeutic effect |
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