| 三种化疗方案治疗进展期胃癌的成本效果分析 |
| 投稿时间：2006-12-25 点此下载全文 |
| 引用本文：刘懿萱,章琎,陈盛新,李捷玮.三种化疗方案治疗进展期胃癌的成本效果分析[J].药学实践杂志,2007,(2):117~120 |
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| 中文摘要:目的:总结探讨不同化疗方案治疗进展期胃癌的成本效果比。方法:收集上海长海医院普外科2003年6月至2004年6月间收治的96例进展期胃癌患者的治疗数据。根据用药方案的不同,分成3组:A组32例(多西他赛+顺铂+5-氟尿嘧啶+亚叶酸钙);B组30例(盐酸表柔比星+顺铂+5-氟尿嘧啶+亚叶酸钙);C组34例(奥沙利铂+5-氟尿嘧啶+亚叶酸钙),运用成本效果分析方法对三种化疗方案进行经济学评价。结果:在三种化疗药物治疗方案中,多西他赛组有效率为56．25%,1个疗程的治疗成本为9979元,成本效果比177．40(元/百分之一有效率);盐酸表柔比星组有效率为40．00%,1个疗程的治疗成本为4158元,成本效果比103．95(元/百分之一有效率);奥沙利铂组有效率为52．94%,1个疗程的治疗成本为4498元,成本效果比84．96(元/百分之一有效率)。增量成本效果分析表明,A组的(⊿C/⊿E)为358．22;C组的(⊿C/⊿E)为26．28。结论:C方案是三种化疗方案治疗进展期胃癌的最合理方案。 |
| 中文关键词:药物经济学 成本效果分析 胃癌 化疗 |
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| Cost-effectiveness analysis of three chemotherapeutic schemes for advanced gastric cancer |
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| Abstract:Objective:To explore the cost-effectiveness of different chemothrapeutic schemes in the treatment of advanced gastric cancer.Methods:96 cases of gastric cancer were divided into three groups receiving different medication.A group(32 cases)with Do-cetaxel+Fluorouracil(5-FU)+Calcium folinate(CF)+Cisplatin(DDP);B group(30 cases)with Epirubicin+DDP+5-FU+CF; C group(34 cases)with Oxaliplatin+5-FU+CF.Date was evaluated using clinic economics cost-effectiveness analysis.Results:A-mong three groups,the effective rate of A group was 56.25% and expenditure of one therapeutic course was 9979 yuans,1% increase of effective rate 177.40 yuans.The effective rate of A group was 40.00% and expenditure of one therapeutic course was 4158 yuans, increase of 1% effective rate was costed 103.95yuans.The effective rate of C group was 52.94% and expenditure of one therapeutic course was 4498 yuans,1% increase of effective rate costed 84.96 yuans.Conclusion:C schemes is the most rational one among three chemotherapeutic programs for advanced gastric cancer. |
| keywords:pharmacoeconomics cost-effectiveness analysis gastric cancer chemotherapy |
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