| 褶合光谱法考察乳酸环丙沙星与常用注射液的配伍稳定性 |
| 投稿时间：2006-02-22 点此下载全文 |
| 引用本文：李国清,李抒诗,高金波,刘研.褶合光谱法考察乳酸环丙沙星与常用注射液的配伍稳定性[J].药学实践杂志,2006,(5):291~293 |
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| 中文摘要:目的：考察室温下8h内乳酸环丙沙星与7种常用注射液的配伍稳定性。方法：采用褶合光谱法, 结合外观和pH值检查法, 并以差谱值予以定量表达。结果：在8h内乳酸环丙沙星和乳酸钠注射液配伍外观有变化, 其余配伍溶液外观均无变化；pH值较稳定。用褶合光谱法考察结果乳酸环丙沙星与6种常用输液配伍的差谱值均＜10%, 与乳酸钠注射液配伍1～8h的差谱值均大于20%。结论：室温8小时内, 除乳酸环丙沙星与乳酸钠注射液不可以配伍使用外, 与其他6种常用输液是可以配伍使用的。 |
| 中文关键词:褶合光谱法 乳酸环丙沙星 药物配伍稳定性 常用输液 |
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| Observation of the stability of common injections mixed with ciprofloxacin lactate by convolution spectrometry |
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| Abstract:Objective:To observe the chemical stability of seven common injections mixed with ciprofloxacin lactate at room tem-perature for 8 hours.Methods:The appearance of mixed injection was observed and pH was tested.The convolution spectrometry was used.The results were described quantitatively by subtract spectrometry value.Results:The subtract spectrometry values of ciprofloxa-cin mixed with six infusions were less than 10%.The subtract spectrometry values of ciprofloxacin lactate mixed with sodium lactate in-jection were 1.57%, 31.76%, 26.46%, 22.85% in 2～8hours.Conclusion:At room temperature for 8 hours ciprofloxacin mixed with six infusions can be used, and ciprofloxacin lactate mixed with sodium lactate injection can't be used. |
| keywords:convolution spectrometry observation of stability of drugs ciprofloxacin lactate infusions |
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