| 氧氟沙星漱口液的研制及稳定性考察 |
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| 引用本文：杨忠东,肖华.氧氟沙星漱口液的研制及稳定性考察[J].药学实践杂志,2006,(5):285~288 |
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| 中文摘要:目的：配制氧氟沙星漱口液, 并考察其稳定性。方法：通过参考有关资料确定处方、制备方法, 并采用紫外分光光度法测定其氧氟沙星含量, 采用初均速法考察其稳定性。结果：初均速法考察稳定性, 线性关系良好, 预测其室温有效期为t0．9=310d。氧氟沙星回收率为99．6%, RSD=2．0%（n=5）。结论：该制剂稳定性良好, 可作为临床辅助治疗药物。 |
| 中文关键词:氧氟沙星 漱口液 稳定性 |
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| Studies on ofloxacin gargle preparation and its stability |
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| Abstract:Objective:To prepare ofloxacin gargle and observe its stability.Methods:Referring to relative literature, the formula and preparing procedure of ofloxacin gargle were established, the stability of the gargle was observed by using initial average rate meth-od.Results:The linear relationship was good in the initial average rate method.The expective effective time at room temperature (t0.9) was was more than 310 days.Ofloxacin's recycle rate was 99.6%.Conclusion:The preparation has good stability, and can be used as clinical therapeutic medicine. |
| keywords:ofloxacin gargle stability |
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