头孢他美酯治疗急性泌尿系统感染临床疗效分析
投稿时间:2006-03-16    点此下载全文
引用本文:贾国强,郭蔚,杨亚青.头孢他美酯治疗急性泌尿系统感染临床疗效分析[J].药学实践杂志,2006,(3):161~163
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作者单位
贾国强 解放军总医院第二临床药局,北京100853 
郭蔚 解放军总医院第二临床药局,北京100853 
杨亚青 解放军总医院第二临床药局,北京100853 
中文摘要:目的:分析头孢他美酯(cefetamet pivoxil)治疗急性泌尿系统感染的临床疗效。方法:20例急性泌尿系统感染患者随机分为两组,分别使用头孢他美酯和阿莫西林-克拉维酸钾片(奥格门,Augmemtin)治疗。 A组:头孢他美酯治疗(n=10),每次250mg,早、晚饭后各服1次,B组:阿莫西林-克拉维酸钾片治疗(n=10),每次375mg,每日3次,饭后服用。两组疗程均为 7d。对有效率、痊愈率,尿中白细胞清除率等方面进行评价。结果:两组治疗有效率分别为80%和90%;痊愈率分别为70%和80%;尿中白细胞的清除率分别为70%和80%。治疗中B组发生副反应1例。经统计分析,A、B两组间的药效及安全性无显著差异(P>0.05)。结论:头孢他美酯是治疗急性泌尿系统感染的有效药物,值得临床推广使用。
中文关键词:头孢他美酯  阿莫西林-克拉维酸钾片  急性泌尿系统感染
 
Analysis of clinical curative effects of cefetamet pivoxil on acute urinary system infected patients
Abstract:Objective: To analyze the clinical curative effects of cefetamet pivoxil on acute urinary system infected patients. Methods:20 acute urinary system infected patients were randomly divided into two groups: group A(n= 10), in which the patients were treated with cefetamet pivoxil(250mg, po, bid, pc) for 7 days, and group B(n= 10), in which the patients were administrated with amoxicillin-clavulante (375mg, po, tid, pc) for7days. The clinical effective rate, recovery rate and WBC clearance rate in urine were statistically evaluated. Results: The clinical effective rates of group A and group B were 80% and 90%, respectively. The recovery rates of group A and group B were 70% and 80%, respectively. The WBC clearance rates in urine of group A and group B were 70% and 80%, respectively. One side effect case occurred in group B. There was no significant difference statistically between two groups (P > 0.05). Conclusion: Cefetamet Pivoxil is efficient to treat acute urinary tract infection.
keywords:cefetamet pivoxil  amoxicillin-clavulante  acute urinary tract infection
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