| 绘制伪三元相图制备卵磷脂液晶的研究 |
| 投稿时间：2005-11-01 点此下载全文 |
| 引用本文：储藏,高静,鲁莹,丁雪鹰,高申.绘制伪三元相图制备卵磷脂液晶的研究[J].药学实践杂志,2006,(3):142~144 |
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| 中文摘要:目的:绘制伪三元相图,对不同纯度卵磷脂及卵磷脂与无水乙醇以不同比例Km形成的液晶区域进行研究。方法:使用不同纯度的卵磷脂作为表面活性剂,无水乙醇为助表面活性剂,十四酸异丙酯为油相制备液晶。使用自制偏光显微镜对液晶结构进行考察,绘制伪三元相图。结果:偏光显微镜下可观察到发亮区域为液晶形成区域。卵磷脂与无水乙醇的比例Km值较低时(1:4),系统没有液晶出现;在25℃及相同Km条件下,使用高纯度卵磷脂作为表面活性剂所形成的液晶区域明显大于使用低纯度卵磷脂所形成的液晶区域; Km值越大,液晶产生的区域越大;同时随着Km值的加大,系统中水的比例范围也随之增大。结论:通过绘制伪三元相图,可以清楚直观地反映出卵磷脂的各组成成分对于液晶形成的影响。 |
| 中文关键词:液晶 伪三元相图 偏光显微镜 卵磷脂 |
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| Pseudo-ternary phase diagrams of lecithin liquid crystal |
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| Abstract:Objective: To construct pseudo-ternary phase diagrams of liquid crystal (LC) with lecithin of various purity and various ratio of lecithin to alcohol (Km). Methods: LC was prepared with lecithin of various purity as surfactant, isopropyl myristate as oil phase and anhydrous alcohol as co-surfactant. The LC configuration was determined with self-made polarization microscope. Results: The liquid crystal formation region was observed light with the polarization microscope. No liquid crystal appeared when the Km was 1 : 4, and in the same condition of 25℃ and Km, the liquid crystal formation region was larger with the lecithin purity increasing. At the same time, the changeable region of water proportion was also larger with the Km increasing. Conclusion: Constructing pseudo-ternary phase diagrams to discribe the factors of liquid crystal configuration is precise and simple. |
| keywords:liquid crystal pseudo-ternary phase diagrams polarization microscope lecithin |
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