吸收系数法测定吡嗪酰胺片中溶出度的研究 |
投稿时间:2005-05-16 点此下载全文 |
引用本文:刘海英,王秀琴,张波,杨宁.吸收系数法测定吡嗪酰胺片中溶出度的研究[J].药学实践杂志,2005,(6):369~370 |
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中文摘要:目的 建立吸收系数法测定吡嗪酰胺片中的溶出度.方法 采用紫外分光光度中的吸收系数法,吸收系数E1cm1%为652.结果 本法与对照品法无显著性差异.结论 本方法简便易行、快速、准确,可作为该制剂的质量控制方法. |
中文关键词:吡嗪酰胺片 吸收系数法 溶出度测定 |
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Determination of dissolution of pyrazinamide tablets by absorption coefficient method |
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Abstract:Objective To establish an absorption coefficient method for determination of the dissolution of Pyrazinamide tablets. Methods The ultraviolet-spetrophotometry-absorptivity(652) was used. The absorption coefficient (E1cm1%) was 652. Results There is no significent difference between absorption coefficient method and standard method. Conclusion The method is simple, quick and accurate. It can be accepted for the quality control of pyrazinamide tablets. |
keywords:pyrazinamide tablets absorption coefficient determination of dissolution |
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