补肾壮骨胶囊对氢化可的松引起骨质疏松症雄性大鼠生化指标的影响 |
投稿时间:2002-01-23 点此下载全文 |
引用本文:李昇刚,杨晓峰,于德志,朱爱民.补肾壮骨胶囊对氢化可的松引起骨质疏松症雄性大鼠生化指标的影响[J].药学实践杂志,2002,(4):226~227 |
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中文摘要:目的 了解补肾壮骨胶囊对氢化可的松引起骨质疏松症雄性大鼠生化指标的影响。方法 采用临床检验方法测定补肾壮骨胶囊对氢化可的松引起骨质疏松症雄性大鼠血清钙、磷、血清碱性磷酸酶的影响。结果 与空白对照组相比,模型对照组的血钙、血磷显著下降,碱性磷酸酶升高。与模型对照组相比,补肾壮骨胶囊高、低剂量组血钙、血磷显著升高,碱性磷酸酶下降。结论 补肾壮骨胶囊对氢化可的松引起雄性大鼠骨质疏松症有明显的防治作用。 |
中文关键词:补肾壮骨胶囊 氢化可的松 骨质疏松 |
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Effects of Bushenzhuanggu capsule on biochemical markers in hydrocortisoneinduced osteoporotic male rats |
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Abstract:OBJECTIVE To study effects of Bushenzhuanggu capsule on biochemical markers in hydrocortisone-induced osteoporotic rat models. METHODS The blood concentrations of calcium, phosphorus and ALP of hydrocortisone-induced osteoporotic rats were determined by clinical biochemical assay. RESULTS After treatment with Bushenzhuanggu capsule, the blood concentrations of calcium, phosphorus and ALP of hydrocortisone-induced osteoporotic rats were increased, the activity of ALP was decreased. CONCLUSION Bushenzhuanggu capsule has some therapeutic effects on hydrocortisone-induced osteoporotic rat models. |
keywords:Bushenzhuanggu capsule hydrocortisone osteoporosis |
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