旋光法和紫外分光光度法测定卡地滴眼液含量 |
投稿时间:2001-07-19 点此下载全文 |
引用本文:李伊庆,王海燕,姜宗文.旋光法和紫外分光光度法测定卡地滴眼液含量[J].药学实践杂志,2002,(3):174~176 |
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中文摘要:目的 建立卡地滴眼液的含量测定方法。方法 用旋光法测定卡地滴眼液中卡那霉素的含量,用紫外分光光度法测定卡地滴眼液中地塞米松磷酸钠的含量。结果 在 1.0~5.0mg·ml-1范围内旋光度与卡那霉素的浓度呈线性关系 (r=0.9999),回收率平均为 99.3%,RSD=0.40% (n=5);在 6~21μg·ml-1范围内吸收度与地塞米松磷酸钠的浓度呈线性关系 (r=0.9998,n=6),回收率平均为 99.2%,RSD=0.20% (n=5).结论 本法简便、快速、准确,适用于医院制剂的快速检验。 |
中文关键词:旋光法 紫外分光光度法 卡那霉素 地塞米松磷酸钠 滴眼液 |
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Assay of kanamycin and dexamethson in DICA eye drops by polarmetric analysis and ultraviolet specyrophotometry |
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Abstract:OBJECTIVE To establish a methed for determining the concentration of kanamycin and dexamethson in DICA eye drops.METHED The concentration of kanamycin was determined by polarmetric analysis,ultravio specyro-photometry was employed for determination of dexamethson sodium phosphate.RESUITS:The average recovery of kana-mycin was 99.3%,RSD=0.40%(n=5);the average recovery of dexamethson sodium phosphate was 99.2%,RSD=0.20%(n=5).CONCLUSION It is a simple method for the quantitative analysis of compound preperation. |
keywords:polarmetric analysis ultraviolet specyrophotometry kanamycin dexamethson sodium phosphate eye drops |
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