| 复方醋酸氟轻松软膏含量测定方法的改进 |
| 投稿时间：2002-01-15 点此下载全文 |
| 引用本文：杨锡祥,谷莉.复方醋酸氟轻松软膏含量测定方法的改进[J].药学实践杂志,2002,(3):171~173 |
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| 中文摘要:目的 改进复方醋酸氟轻松软膏含量测定方法。方法 采用RP-HPLC法,提取过滤后加内标。ODS柱 (250mm× 4.6mm,5μm),以甲醇-水-乙醚 (62:38:2,v/v/v)为流动相,检测波长为 240nm,流速为 1.0ml·min-1.结果 改进后的方法精密度及准确度均较满意。结论 改进后的方法解决了原方法存在的问题,对软膏剂的含量测定具有普遍意义。 |
| 中文关键词:复方醋酸氟轻松 高效液相色谱法 软膏 |
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| The improve of the method for determination compound fluocinonide ointment |
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| Abstract:OBJECTIVE To improve the method for determination compound fluocinonide ointment.METHODS A method of RP HPLC be used, plus the internal standard after extraction and filter.ODS column (250mm×4.6mm, 5μm) was selected and the mobile phase was consisted of methanol-water-ether(62:38:2,v/v/v) at flow rate of 1.0ml·min-1.The detection wavelength was 240nm.RESULTS The precision and the accuracy of improved method are good.CONCLUSION The problem of the old method was solved with this improved method and have a universal significance for the determination of ointment preparation. |
| keywords:compound fluocinonide RP-HPLC ointment |
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