双波长分光光度法测定复方萘酚喹片中甲氧苄啶含量 |
投稿时间:2001-06-13 点此下载全文 |
引用本文:肖文中,张美义,林燕芳,詹利之,符林春,李国桥.双波长分光光度法测定复方萘酚喹片中甲氧苄啶含量[J].药学实践杂志,2001,(6):354~355,331 |
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中文摘要:目的 建立复方萘酚喹片中甲氧苄啶含量测定的方法。方法 测定波长为271nm,参比波长为361nm。结果 线性范围为6.24~31.20μg/ml,r=0.9999(n=6),平均回收率为100.9%,RSD为0.24%(n=6).结论 该法操作简便、快捷、准确,适用于其含量和溶出度的测定。 |
中文关键词:双波长分光光度法 磷酸萘酚喹 甲氧苄啶 复方制剂 |
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Determination of trimethoprim in compound naphthoquine tablets by di-wavelength spectrophotosmetry |
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Abstract:OBJECTIVE To develop a method for determination of trimethoprim in compound naphthoquine Tablets.METHODS Detected at 271nm, with referenced wavelength at 361nm. RESULTS Within 6.24~31.20μg/ml, TMP had a good linearity (r=0.9999).The average recovery was 100.9%, with the RSD of 0.24%(n=6).CONCLUSION The method was simple, rapid, accurate, and can be used both as the determination of content and the determination of dissolve. |
keywords:di-wavelength spectrophotosmetry naphthoquine phosphate trimethoprim compound preparation |
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