| 高三尖杉酯碱与恩丹西酮、格拉司琼配伍的稳定性考察 |
| 投稿时间：2001-05-14 点此下载全文 |
| 引用本文：彭显平,徐贵丽,牟冰,杨艳,庞云丽.高三尖杉酯碱与恩丹西酮、格拉司琼配伍的稳定性考察[J].药学实践杂志,2001,(6):332~333 |
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| 中文摘要:目的 研究高三尖杉酯碱分别与两种止吐药恩丹西酮、格拉司琼在生理盐水中配伍的稳定性。方法 采用紫外分光光度法考察高三尖杉酯碱与恩丹西酮、格拉司琼在 8h内的吸收度变化情况,同时观察外观、pH值及薄层层析检查。结果 在室温条件下,高三尖杉酯碱与恩丹西酮、格拉司琼在0～8h内外观、特征峰吸收度、pH值无明显变化,薄层层析检查无新物质产生。 结论 高三尖杉酯碱与恩丹西酮、格拉司琼在生理盐水中可以配伍使用。 |
| 中文关键词:高三尖杉酯碱 恩丹西酮 格拉司琼 药物配伍 紫外分光光度法 |
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| The compatibility of homoharringtonine with ondansetron,granisetron |
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| Abstract:OBJECTIVE To study the compatible stability of homoharringtonine with two kinds of stoping vomit drugs(granisetron,ondansetron)in 0.9% NaCl solution.METHODS The compatible content was investigated in 8 hour after mixed of homohrringtonine with above-mentioned two kind of stoping vomit drugs by ultrariolet spectrophotometry.At the same time,the pH and TLC were determined.RESULTS There were no evident changes in appearance,pH and spectrum at room temperature 25℃ within 0～8 hours. There were no new substances formed by TLC.CONCLUSIONS Homoharringtonine with grarinsetron,ondansetron in 0.9% NaCl can be used. |
| keywords:homoharringtonine granisetron ondansetron compatibility stability |
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