| 甲磺酸甲氟哌酸糖衣片溶出度测定方法考察 |
| 投稿时间：2001-03-30 点此下载全文 |
| 引用本文：李革晖.甲磺酸甲氟哌酸糖衣片溶出度测定方法考察[J].药学实践杂志,2001,(5):293~295 |
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| 中文摘要:目的 对甲磺酸甲氟哌酸糖衣片体外溶出度测定方法进行考察,为评定和控制药品内在质量提供依据。方法 采用紫外法对甲磺酸甲氟哌酸糖衣片溶出度进行测定,并对转篮法和浆法两种测定方法进行了比较。结果 两种测定方法的溶出参数T50、Td、m经成组比较t检验,差异显着(P<0.01)。结论 使用转篮法测甲磺酸甲氟哌酸糖衣片效果较好。 |
| 中文关键词:甲磺酸甲氟哌酸片 溶出度 紫外分光光度法 |
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| Dissolution study of pefloxacin tablets |
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| Abstract:OBJECTIVE To study the dissolution of pefloxacin tables. METHODS The dissolution rate of pefloxacin tablets was determined by ultraviolet spectrophotometry. At the same time, rotating basket method and oaring method ware compared. RESULTS There was signifficant difference (P<0.01) in T50 and Td between rotating basket method and oaring method. CONCLUSION Using rotating basket method to test dissolution is better than using oaring method. |
| keywords:pefloxacin tablet dissolution ultraviolet spec trophotometry |
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