静肤平中甲硝唑与红霉素的含量测定
投稿时间:2000-12-25    点此下载全文
引用本文:王碧江,金城,罗东.静肤平中甲硝唑与红霉素的含量测定[J].药学实践杂志,2001,(4):229~230
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作者单位
王碧江 第三军医大学西南医院药剂科, 重庆400038 
金城 第三军医大学西南医院药剂科, 重庆400038 
罗东 第三军医大学西南医院药剂科, 重庆400038 
中文摘要:目的 建立用比色法与分光光度法测定静肤平中红霉素、甲硝唑含量的方法 。方法 以稀盐酸(9→1000)溶液为溶剂,在417nm,277nm波长处进行测定。结果 红霉素在5.0~20.0μg/ml浓度范围内线性关系良好。红霉素的平均回收率为98.55%,RCD为0.52%(n=5),甲硝唑的平均回收率为98.86%,RCD为0.51%(n=5).结论 本方法简便快捷、准确,制剂中的其他成分不干扰测定。
中文关键词:静肤平  甲硝唑  红霉素  分光光度法  比色法
 
Determination of metronidazolum and erythromycin in Jing-fu-ping liqour
Abstract:OBJECTIVE To estabish a quantiative analysis for Jing fu ping liqour.METHODS Jing fu ping liquor was determined in 0.1mol/L HCl.The wavelength of detection were 417nm and 277nm.RESULTS There were good linear correlation in the range of erythromycin(5.0~20.0μg/ml) and metronidazolum(2.0~15.0μg/ml),the average recovery and relative standard deviation were 98.55% and 0.52%(n=5) for erythromycin 98.86% and 0.51%(n=5) for metronidazolum.CONCLUSIONS The method is simple,rapid and auurate.
keywords:Jing-fu-ping  colorimetry  erythromycin  spectraphotometry  metronidazolum
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