| 高效液相法测定解热抗炎Ⅰ号口服液中厚朴酚含量 |
| 投稿时间：2000-08-02 点此下载全文 |
| 引用本文：房志仲,杨金荣,李鑫,李璐,张庆伟,刘茂军.高效液相法测定解热抗炎Ⅰ号口服液中厚朴酚含量[J].药学实践杂志,2001,(2):96~98 |
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| 中文摘要:目的 对解热抗炎Ⅰ号口服液中厚朴的有效成分厚朴酚进行定性、定量分析,建立质控方法。方法 用薄层层析法对有效成分厚朴酚进行定性分析,以高效液相色谱法在ODS-C18柱上以甲醇-水(70:30)为流动相测定其含量。结果 厚朴酚的回收率为98.15%(RSD=2.96%),检测范围为0.0184～0.184μg/ml,r =0.9996。可以作为该制剂的质控方法。结论 所用定性、定量方法快速、可靠、灵敏。 |
| 中文关键词:口服液 厚朴酚 薄层层析法 高效液相色谱法 |
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| Determination of magnolol in Jierekangyan No.I oral solution by HPLC |
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| Abstract:OBJECTIVE To establish a method of quality control for Jierekangyan No.1(JRKY) oral solution by qualitatively and quantitatively determining the active substance of magnolol in the solution.METHODS Analyse magnolol qualitatively by TLC and quantitatively on ODS-C18 column with MeOH-water(70:30) as mobile phase,to determine the content of magnolol by HPLC.RESULTS The average recovery was 98.15%(RSD=2.96%).The linear concentration range of the method was 0.0148～0.148μg/ml, r =0.9996.CONCLUSION The qualitative and the quantitative methods studied are rapid,reliable and sensitive. |
| keywords:oral solution magnolol TLC HPLC |
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