| 治疗药物监测进展 |
| 投稿时间：1999-11-26 点此下载全文 |
| 引用本文：马骏,谢景文,孙卫胜,谢华,贾正平,刘静.治疗药物监测进展[J].药学实践杂志,2000,(4):250~254,244 |
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| 基金项目:全军"九五"医学科研规划第二批科研基金面上项目,编号98M018 |
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| 中文摘要:目的 阐述治疗药物监测的必要性和测定技术。方法 对所监测的药物、取样和分析方法进行综述。结果 说明了药物监测的范围和指标,样品需求的条件,重点比较了色谱技术和免疫分析法在TDM中的应用和各自的优越性。结论 确保TDM的顺利进行,必须具备临床知识和掌握分析技术。 |
| 中文关键词:治疗药物监测 色谱法 免疫分析法 |
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| Development of therapeutic drug monitoring |
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| Abstract:OBJECTIVE To review the principles of therapeutic drug monitoring (TDM)and the role of analytical techniques in TDM.METHODS The content included ranges of monitored drugs,sampling requirements and analytical aspects.RESULTS This article explained the criteria for undertaking drug level monitoring and the requirements of sampling,compared techniques of chromatographic and immunoassay.CONCLUSION For reliable results of TDM,it is necessary to implement good quality control of the assay to ensure that it continues to work satisfactorily. |
| keywords:therapeutic drug monitoring chromalography immunoassay |
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