| 治疗砷中毒制剂砷肤灵软膏的毒性观察 |
| 投稿时间：1999-10-06 点此下载全文 |
| 引用本文：任渝江,张爱华,王宝佳,林芳.治疗砷中毒制剂砷肤灵软膏的毒性观察[J].药学实践杂志,2000,(3):147~149 |
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| 基金项目:国家自然科学基金,资助号39660070 |
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| 中文摘要:目的 评价砷肤灵(主含维甲酸、二巯基丙醇、水杨酸等)软膏的皮肤安全性。方法 常规急性毒性实验和皮肤粘膜刺激性实验。结果 砷肤灵无皮肤吸收毒性,对皮肤粘膜及眼结合膜有轻度刺激,对皮肤不引起过敏反应。结论 本制剂无毒性,可供砷中毒所致掌趾角化患者使用。 |
| 中文关键词:砷肤灵 毒性 刺激性 过敏反应 |
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| The observation of toxicity of Shenfuling ointment |
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| Abstract:OBJECTIVE To measure the safety of Shenfuling(made from tretinoin、dimercaprol and salicylic acid)ointment.METHODS Acute toxicity tests and stimulation tests for skin and mucosa were used. RESULTS Shenfuling ointment had no toxicity and hypersentivity of skin and lower stimulation for skin and eyes.CONCLUION Shenfuling ointment has no toxicity.It can be used in the paitient of chronic arsenic poisoning. |
| keywords:Shenfuling ointment toxicity stimulation hypersensitivity |
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